The Global Burden of Liver Disease

~~ Dr Wey George Danlami Consultant-Family Physician Liver disease is a major global health concern, causing over two million deaths annually. This high mortality rate is primarily driven by cirrhosis, viral hepatitis, and liver cancer, which collectively account for 4% of all global deaths. A significant proportion of these deaths occur in women. Key Causes and Risk Factors: Alcohol-Related Liver Disease (ALD): Excessive alcohol consumption is a leading cause of cirrhosis worldwide, especially in high-income countries. Alcohol use disorder (AUD) dramatically increases the risk of liver-related mortality, and this risk is projected to rise due to increasing alcohol use and an aging population. Non-Alcoholic Fatty Liver Disease (NAFLD): Affecting approximately one-quarter of the global adult population, NAFLD is a significant contributor to liver failure and the need for liver transplantation, particularly in developed nations. Its strong associ...